France scientists detect new COVID-19 variant carrying 46 mutations

France scientists detect new COVID-19 variant carrying 46 mutations

Lara Adejoro<

Scientists in France have identified a potentially worrying new variant, named IHU, the new B.1.640.2 variant has so far infected 12 people living in southeastern France. 

The first case was linked to a person with a travel history to Cameroon.

The mutant strain has 46 mutations that are thought to make it both more vaccine-resistant and infectious than the original virus.

The strain was discovered by academics based at the IHU Mediterranee Infection on December 10 but has not spread rapidly since.

Professor Philippe Colson, who heads up the unit that discovered the strain, said: ‘We indeed have several cases of this new variant in the Marseille geographical area.

‘We named it “variant IHU”. Two new genomes have just been submitted,” Daily Mail reports.

The variant has been dubbed B.1.640.2 and its discovery was announced in a paper posted on medRxiv. This has not been published in an academic journal.

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Scientists say the lineage is genetically different to B.1.640, which is thought to have emerged in the Democratic Republic of Congo in September.

Tests show the strain carries the E484K mutation that is thought to make it more resistant to vaccines.

It also has the N501Y mutation — first seen on the Alpha variant — that experts believe can make it more transmissible.  

It is a distant relative of Omicron, which scientists say likely evolved from an older virus.

The scientists say in their paper: “These observations show once again the unpredictability of the emergence of new SARS-CoV-2 variants and their introduction from abroad.

“And they exemplify the difficulty to control such introduction and subsequent spread.”



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